Dr. Idan Menashe received a B.Sc. in Medical Lab Sciences with a roll of distinction from the Ben Gurion University, Beer-Sheva, Israel in 1999. He then continued his studies at the Feinberg Graduate School in the Weizmann Institute of Science, Rehovot, Israel, where he received an M.Sc. in Population Genetics (2001), and a Ph.D in Human Genetics and Bioinformatics (2006). During his dissertation research, Dr. Menashe identified a unique set of olfactory receptor segregating pseudogenes and demonstrated that one of them (OR11H7P) determines human’s specific hypersensitivity to the sweaty odor of isovaleric acid. In January 2007, Dr. Menashe joined the Division of Cancer Epidemiology and Genetics (DCEG) as visiting fellow in Biostatistics. During his fellowship, he was involved in multiple descriptive and analytical studies of cancer epidemiology with an emphasis on pathway analysis of large-scale genetic data, and cancer racial disparities.
In October 2011, Dr. Menashe joined MindSpec as a Bioinformatics Scientist. At MindSpec he conducts genetic and epidemiological studies of Autism Spectrum Disorders (ASD), and writes to the’ Trends’ section of the Autism Reading Room. Dr. Menashe has published many research articles in a broad range of scientific journals and was the recipient of various national and international awards.
(Selected list of 10 most recent articles; for full list see Google and PubMed links above)
Menashe I, Figueroa JD, Garcia-Closas M, Chatterjee N, Malats N, Picornell A, Maeder D, Yang Q, Prokunina-Olsson L, Wang Z, Real FX, Jacobs KB, Baris D, Thun M, Albanes D, Purdue MP, Kogevinas M, Hutchinson A, Fu YP, Tang W, Burdette L, Tardón A, Serra C, Carrato A, García-Closas R, Lloreta J, Johnson A, Schwenn M, Schned A, Andriole G Jr, Black A, Jacobs EJ, Diver RW, Gapstur SM, Weinstein SJ, Virtamo J, Caporaso NE, Landi MT, Fraumeni JF Jr, Chanock SJ, Silverman DT, Rothman N (2012). Large-scale pathway-based analysis of bladder cancer genome-wide association data from five studies of European background. PLoS One 7:e29396.
Bassig BA, Zheng T, Zhang Y, Berndt SI, Holford TR, Hosgood HD 3rd, Hu W, Leaderer B, Yeager M, Menashe I, Boyle P, Xu J, Zou K, Zhu Y, Chanock S, Rothman N, Lan Q (2012). Polylmorphisms in complement system genes and risk of non-Hodgkin lymphoma. Environ Mol Mutagen. 53:145-51.
Meyer TE, Chu LW, Li Q, Yu K, Rosenberg PS, Menashe I, Chokkalingam AP, Quraishi SM, Huang WY, Weiss JM, Kaaks R, Hayes RB, Chanock SJ, Hsing AW (2012). The association between inflammation-related genes and serum androgen levels in men: The prostate, lung, colorectal, and ovarian study. The Prostate 72(1):65-71.
Kumar A, Swanwick CC, Johnson N, Menashe I, Basu SN, Bales ME, Banerjee-Basu S (2011). A brain region-specific predictive gene map for autism derived by profiling a reference gene set. PLoS One 6:e28431.
van Bemmel DM, Boffetta P, Liao LM, Berndt SI, Menashe I, Yeager M, Chanock S, Karami S, Zaridze D, Matteev V, Janout V, Kollarova H, Bencko V, Navratilova M, Szeszenia-Dabrowska N, Mates D, Slamova A, Rothman N, Han SS, Rosenberg PS, Brennan P, Chow WH, Moore LE (2011). Comprehensive analysis of 5-aminolevulinic acid dehydrogenase (ALAD) variants and renal cell carcinoma risk among individuals exposed to lead. PLoS One 6:e20432.
Lan Q, Wang SS, Menashe I, Armstrong B, Zhang Y, Hartge P, Purdue MP, Holford TR, Morton LM, Kricker A, Cerhan JR, Grulich A, Cozen W, Zahm SH, Yeager M, Vajdic CM, Schenk M, Leaderer B, Yuenger J, Severson RK, Chatterjee N, Chanock SJ, Zheng T, Rothman N (2011). Genetic variation in Th1/Th2 pathway genes and risk of non-Hodgkin lymphoma: a pooled analysis of three population-based case-control studies. Br J Haematol 153:341-350.
Lozier J, Rosenberg PS, Goedert JJ, and Menashe I (2011). A Case-Control Study of Candidate Immunoregulatory Genes Reveals Haplotypes That Influence Inhibitor Risk in Severe Hemophilia A. Haemophilia 17(4):641-9.
Hosgood HD 3rd, Purdue MP, Wang SS, Zheng T, Morton LM, Lan Q, Menashe I, Zhang Y, Cerhan JR, Grulich A, Cozen W, Yeager M, Holford TR, Vajdic CM, Davis S, Leaderer B, Kricker A, Schenk M, Zahm SH, Chatterjee N, Chanock SJ, Rothman N, Hartge P, Armstrong B (2011). A pooled analysis of three studies evaluating genetic variation in immune-related genes and non-Hodgkin lymphoma risk. Br J Haematol 152(6):721-6.
Wang SS, Menashe I, Cerhan JR, Cozen W, Severson RK, Davis S, Hutchinson A, Rothman N, Chanock SJ, Bernstein L, Hartge P, Morton LM (2010. Variations in chromosomes 9 and 6p21.3 with risk of non-Hodgkin lymphoma. Cancer Epidemiol Biomarkers Prev. 20:42-9.
Purdue MP, Lan Q, Menashe I, Zheng T, Zhang Y, Yeager M, Hosgood HD 3rd, Zahm SH, Chanock SJ, Rothman N, Baris D (2011). Variation in innate immunity genes and risk of multiple myeloma. Hematol Oncol. 29(1):42-6.